FBackup can backup open/locked files and it can perform full and mirror backups (backup type that does not compress the files). When defining a backup you can also set file filters and schedule the backup for automatic execution.
You can run predefined backups, such as My Documents, My Pictures or Outlook Express and load backup plugins that will back up the settings and data of specific applications (full list of existing backup plugins at www.backup4all.com/backup-plugins.php ).
FBackup has ZIP64 support (can create backups over 2 GB) and creates standard zip files, meaning that you can access it with any zip compatible utility. FBackup also allows you to password protect your backup.
FBackup tests the backup files automatically to ensure the backup is safe and correctly executed (uses CRC32).
FBackup runs on Windows Vista, XP, 2000 and 2008/2003/2000 Server. FBackup is free for both personal and commercial use.